Last week: 10-6. Season: 113-63.
Line: Bears by 3.5. Over/under: 37.5.
Russell Wilson isn't same quarterback on road he is at home. Bears are saddled with a lot of injuries, but defense still knows how to force turnovers.
Pick: Bears 21, Seahawks 17.
Vikings (6-5) at Packers (7-4), noon
Line: Packers by 9.5. Over/under: 46.5.
During Packers' four-game winning streak over Vikings, Aaron Rodgers has thrown for 1,181 yards with 13 touchdowns and just two interceptions.
Pick: Packers 31, Vikings 27.
Panthers (3-8) at Chiefs (1-10), noon
Line: Panthers by 3. Over/under: 40.5.
Two wins in a row for Panthers? On road, no less? Consider Chiefs have given up at least 26 points five times over their eight-game slide.
Pick: Panthers 20, Chiefs 13.
Cardinals (4-7) at Jets (4-7), noon
Line: Jets by 4.5. Over/under: 36.5.
After their stinker on Thanksgiving, it's hard to imagine Jets winning a game. Then again, Cardinals are in similar tailspin after dropping seven in a row.
Pick: Jets 20, Cardinals 13.
49ers (8-2-1) at Rams (4-6-1), noon
Line: 49ers by 7. Over/under: 40.
Niners are hitting their stride with Colin Kaepernick, and they've won four of five in St. Louis. Rams' best hope is to get Steven Jackson rolling.
Pick: 49ers 24, Rams 20.
Jaguars (2-9) at Bills (4-7), noon
Line: Bills by 6. Over/under: 45.
Teams are pretty evenly matched, with Jaguars getting a little better with Chad Henne and banged-up Bills struggling of late. Being at home counts.
Pick: Bills 24, Jaguars 21.
Colts (7-4) at Lions (4-7), noon
Line: Lions by 5. Over/under: 51.
Bills got to Andrew Luck four times in Colts' last game. Lions will feast on any protection breakdowns, especially when Luck will be throwing often to keep pace.
Pick: Lions 31, Colts 28.
Patriots (8-3) at Dolphins (5-6), noon
Line: Patriots by 9. Over/under: 51.5.
Patriots are averaging 435.8 yards and 37 points. It's tough for any opposing quarterback to respond to that firepower, especially a rookie.
Pick: Patriots 35, Dolphins 24.
Texans (10-1) at Titans (4-7), noon
Line: Texans by 6. Over/under: 47.
Titans' Chris Johnson had a big game last time these teams met, and Texans still won by 24. Playoff-bound Texans are simply a better team.
Pick: Texans 28, Titans 20.
Buccaneers (6-5) at Broncos (8-3), 3:05 p.m.
Line: Broncos by 8. Over/under: 50.
Hot as Buccaneers have been, it's late in season, teams are inching closer to playoffs and Peyton Manning tends to win these kind of games.
Pick: Broncos 28, Buccaneers 24.
Steelers (6-5) at Ravens (9-2), 3:25 p.m., WBBM-Ch. 2
Line: Ravens by 3. Over/under: 40.
This game figures to be close — most in this series are — but Ravens get edge because they're at home and in light of Steelers' shaky quarterback situation.
Pick: Ravens 16, Steelers 13.
Browns (3-8) at Raiders (3-8), 3:25 p.m.
Line: Raiders by 1.5. Over/under: 44.
Browns have lost 11 in a row on road. Raiders, though, are playing horrendous defense. Trent Richardson has ability and opportunity to run wild.
Pick: Browns 21, Raiders 17.
Bengals (6-5) at Chargers (4-7), 3:25 p.m.
Line: Bengals by 1. Over/under: 46.
Among their many problems, Chargers can't get off field on third (or fourth) down. That's a problem when facing Andy Dalton, A.J. Green and Mohamed Sanu.
Pick: Bengals 28, Chargers 27.
Eagles (3-8) at Cowboys (5-6), 7:20 p.m., WMAQ-Ch. 5
Line: Cowboys by 10. Over/under: 43.
Neither team is headed in right direction, but in race to bottom, Eagles are sinking faster than Cowboys, who have at least a shred of hope.
Pick: Cowboys 24, Eagles 20.
Giants (7-4) at Redskins (5-6), 7:30 p.m., ESPN
Line: Giants by 1. Over/under: 51.
Toss out long touchdown pass to Victor Cruz, and Eli Manning has struggled against Redskins in recent years. Robert Griffin III will make most of spotlight.
Pick: Redskins 35, Giants 31.