PEOPLE'S PHARMACY

Drug may cause B-12 deficiency

I am a retired doctor with Type 2 diabetes. Metformin had kept my blood sugar in the normal range for 10 years, but my foot numbness was getting worse. I was also a little unsteady on my feet.

In reviewing medical literature, I discovered that metformin interferes with vitamin B-12. I started oral
vitamin B-12, and within a week I noticed a sharpening of my mental capacity. I stopped having any trouble walking, and my foot numbness has decreased.

Many older diabetics take metformin, and their subtle deficits may be overlooked.

Thank you for pointing out that metformin (Glucophage) can deplete the body of vitamin B-12. This can lead to serious neurological symptoms if not corrected promptly.



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I take fish oil to lower triglycerides. I recently found that it also helps with dry eyes.

A study published in the American Journal of Clinical Nutrition (October 2005) suggests that dry eye syndrome is less common in women who get more omega-3 fats. Fish oil is rich in these fatty acids. Women who consumed more tuna were less likely to complain of dry eyes.



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Is there a self-test for checking your cholesterol? I am trying to get my cholesterol under control with diet, and I want to track my progress.

Over-the-counter cholesterol tests for home use have been around since 1993. But according to Consumer Reports (August 2003), they don't provide enough information to be very helpful.


Joe Graedon, a pharmacologist, and Teresa Graedon, an expert in medical anthropology and nutrition, can be reached at http://www.peoplespharmacy.comor care of this newspaper.